Delayed response to repetitive transcranial magnetic stimulation treatment for intractable auditory hallucinations in schizoaffective disorder

TO THE EDITOR: There have been a small number of treatment trials of low frequency repetitive transcranial magnetic stimulation (rTMS) to the left temporoparietal cortex for chronic, intractable auditory hallucinations (AHs).1 We report a possible “delayed response” to rTMS. rTMS has been demonstrated to be an effective treatment for major depressive disorder (MDD).2 The availability of rTMS varies considerably in different countries. In 2008 the FDA approved the marketing of the NeuroStar TMS therapy device for treating adults with MDD who have failed to achieve satisfactory improvement with prior antidepressant medication.3 The use of rTMS to treat other conditions or symptoms, such as AHs, generally is regarded as experimental…

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