Escitalopram reduces hot flashes in nondepressed menopausal women: A pilot study

BACKGROUND: Hot fl ashes are one of the most troubling manifestations of menopause, affecting about 80% of women. Due to recent controversies about hormone replacement therapy, many women seek alternative treatments. Th e use of antidepressants to treat hot flashes and other menopausal symptoms has been an active area of investigation. However, the majority of past research in this area has included women with significant medical or psychiatric histories that may infl uence treatment response. Th is was the fi rst study to examine the impact of escitalopram on hot fl ashes, mood, sleep, and quality of life in a sample of healthy nondepressed menopausal women.

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