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Alexithymia in oncologic disease: Association with cancer invasion and hemoglobin levels

Antonino Messina, MD

Scuola di Specializzazione in Psichiatria, Università di Catania, Catania, Italy

Anna Maria Fogliani, MD

Scuola di Specializzazione in Psichiatria, Università di Catania, Catania, Italy

Sergio Paradiso, MD, PhD

Department of Psychiatry, University of Iowa, Iowa City, IA, USA

BACKGROUND: The literature suggests that alexithymia is the result of individual differences and/or biological mechanisms. Both individual differences and disease mechanisms may play a role among individuals with medical or surgical conditions. The relative weight of clinical and individual differences factors related to alexithymia has not been studied in patients with cancer. The purpose of this study was to examine the extent to which individual differences in perceived stress and biological markers of illness severity are associated with alexithymia among patients with cancer.

METHODS: Treated oncologic outpatients (N=37) were assessed using the 20-item Toronto Alexithymia Scale and Perceived Stress Scale. Alexithymia was examined in relation to perceived stress, tumor staging, and hemoglobin levels.

RESULTS: Among the patients studied, 34.2% endorsed the established cutoff score (≥61) for alexithymia. Higher alexithymia scores were found in patients with more advanced stages of cancer invasion. Alexithymia correlated directly with perceived stress and indirectly with hemoglobin levels. Hemoglobin levels and cancer invasion significantly correlated with alexithymia when controlling for perceived stress.

CONCLUSIONS: A significant component of alexithymia in cancer patients may be construed as acquired. But awareness of health status influencing perceived stress might partially mediate the role of cancer invasion and hemoglobin on alexithymia.

KEYWORDS: alexithymia, cancer, hemoglobin, perceived stress, personality, tumor staging

ANNALS OF CLINICAL PSYCHIATRY 2011;23(2):125–130

CORRESPONDENCE: Sergio Paradiso, MD, PhD, University of Iowa, Department of Psychiatry, 200 Hawkins Drive, W278 GH, Iowa City, IA 52242 USA E-MAIL: sergio-paradiso@uiowa.edu
Annals of Clinical Psychiatry ©2011 Quadrant HealthCom Inc.

 
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