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A survey study of the satisfaction and attitude of the Korean psychiatrists toward antipsychotic polypharmacy

Jisoon Chang, MD

Department of Psychiatry, Inje University Sanggye Paik Hospital, Seoul, South Korea

Bongseog Kim, MD, PhD

Department of Psychiatry, Inje University Sanggye Paik Hospital, Seoul, South Korea

BACKGROUND: Antipsychotic polypharmacy (AP) to treat patients with schizophrenia and schizoaffective disorder is commonly prescribed in clinical practice; however, evidence supporting its use is scarce. This study surveyed South Korean psychiatrists’ rationale for AP.

METHODS: Psychiatrists were interviewed using a newly developed, semi-structured questionnaire inquiring about AP attitudes and behaviors, including frequency of use, rationale, concerns, and preferred combinations.

RESULTS: Compared with the high-prescribing AP group (≥10 patients a day; HAP group), the low-prescribing AP group (≤9 patients a day; LAP group) tended to work in a university general hospital, publish more research papers a year, attend more psychiatric conferences, prescribe more 2-antipsychotic combinations, and have more satisfaction with AP. Psychiatrists were satisfied with the therapeutic response with AP (rating 6.4±1.5). Psychiatrists felt concern about AP (rating 4.7±1.6), mostly because of its higher risk of chronic adverse effects.

CONCLUSIONS: In South Korean psychiatric practices, the LAP group seems to pay closer attention to AP than the HAP group does. However, both the HAP and LAP groups share similar attitudes toward satisfaction, concerns, and preferred combinations of AP.

KEYWORDS: antipsychotics, polypharmacy, combinations, schizophrenia


CORRESPONDENCE: Bongseog Kim, MD, PhD Department of Psychiatry Inje University Sanggye Paik Hospital Dongil-ro 1342, Nowon-gu Seoul, South Korea E-MAIL: psy.jschang@gmail.com, kimbs328@paik.ac.kr
Annals of Clinical Psychiatry ©2014 Quadrant HealthCom Inc.

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